| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 22/10/26 16:30 | Kairat Almaty | Panathinaikos Athenas | 1:5 |
| 22/10/26 18:45 | FC Nordsjaelland | CSKA Sofía | 2:2 |
| 22/10/26 18:45 | FK Jablonec | Brighton and Hove Albion | 0:0 |
| 22/10/26 18:45 | Getafe C.F. | FC Lugano | 2:5 |
| 22/10/26 18:45 | Trabzonspor | Heart of Midlothian | 2:0 |
| 22/10/26 18:45 | Estrella Roja Belgrado | FC Copenhague | 2:2 |
| 22/10/26 18:45 | FC Iberia 1999 | Mjaellby AIF | 1:1 |
| 22/10/26 18:45 | FK Kauno Zalgiris | Brann Bergen | 1:4 |
| 22/10/26 18:45 | Inter Escaldes | Universitatea Craiova | 1:3 |
| 22/10/26 18:45 | Pafos FC | Riga FC | 1:1 |
| 22/10/26 21:00 | Lincoln Red Imps FC | FC Twente Enschede | 1:4 |
| 22/10/26 21:00 | FK Borac | Kuopion PS | 2:0 |
| 22/10/26 21:00 | FC Midtjylland | Sint-Truidense VV | 0:1 |
| 22/10/26 21:00 | AS Monaco | SC Freiburg | 3:0 |
| 22/10/26 21:00 | Ajax Amsterdam | Atalanta Bergamo | 2:0 |
| 22/10/26 21:00 | Sporting Braga | KAA Gent | 2:0 |
| 22/10/26 21:00 | Aarhus GF | KF Egnatia | 1:1 |
| 22/10/26 21:00 | FC Thun | HNK Hajduk Split | 0:1 |